It's safe for all conditions in which osteoarthritis is a byproduct. You do want to be sure that it's not an issue of a RUPTURED disc, but DJD or other spinal issues is fine. It's primarily arthritis treatment, however, it was discovered that it seemed to help much more than that.
This is by far my favorite pro-Adequan story by Mike Richards, DVM. I quoted this from the last link I posted: I attended a conference a while ago on hematology and blood component therapy. During the dinner break on the first night one of the participants at my table asked the speaker if Adequan (Rx) could cause bleeding tendencies since its structure is somewhat similar to heparin. The speaker replied that he did not know of any problems with that from a clinical perspective but that it conceivably could cause a slight increase in bleeding times. The questioner then asked if anyone at the table was using it for pain relief and anti-inflammatory effects in dogs with arthritis. All of us were trying it. The general consensus at the table was that it seemed to be beneficial in some dogs. One of the vets said "I think it's a wonderful drug but it sure does burn when you inject it". I replied, "I don't really see that effect. I haven't had any dogs really protest the injections and we use a lot of it in our clinic". To which the vet replied, "No, it really does burn" To which I replied, "Really, I am not seeing reactions that make me think that it hurts to inject. Are you sure?" To which the vet replied, while making injection motions into the thigh of his right leg, "I KNOW it burns. AND I can ski again now."
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