I knew about sight hounds being more sensitive to anesthesia, and never thought about it being because of the muscle-fat ratio. It makes total sense, as when you're putting an emaciated animal under..... I just never connected the dots! Geeze, I feel stupid now.... lol.
All the vets I've worked for (as a tech) use Propofol as the primary induction agent. It's safest, and it works... so why not?
Reg: 07-13-2005
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Loc: North-Central coast of California
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Quote: Kelly Byrd
Excellent thread.
I knew about sight hounds being more sensitive to anesthesia, and never thought about it being because of the muscle-fat ratio. It makes total sense, as when you're putting an emaciated animal under..... I just never connected the dots! Geeze, I feel stupid now.... lol.
All the vets I've worked for (as a tech) use Propofol as the primary induction agent. It's safest, and it works... so why not?
I don't think it is just the muscle-fat ratio in sight hounds. There is an across-the-board sensitivity in the sight hound breeds to certain anesthesias, but I think it's a combination of factors, including liver metabolizing. I have something saved about that. More when I find it.
Years ago, I was reading a vet anesthesia specialist's blog and the final recap stayed with me. It was something about (aside from the flat-faced and the sight-hound breeds) the safest anesthesia being the one administered by staff who has a catheter in place and who constantly and with great care monitors the dog's anesthesia reactions .... this being the staff member's only job in the O.R.
Reg: 07-13-2005
Posts: 31571
Loc: North-Central coast of California
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Quote: Connie Sutherland
There is an across-the-board sensitivity in the sight hound breeds to certain anesthesias, but I think it's a combination of factors, including liver metabolizing. I have something saved about that. More when I find it.
The sighthounds are an ancient group of dog breeds that have been selectively bred for high-speed pursuit of prey by sight. Probably as a consequence of this selection process, these dogs have a number of idiosyncrasies that can potentially adversely affect their anesthetic management.
(1) nervous demeanor which can lead to stress-induced clinical complications, such as hyperthermia; (2) lean body conformation with high surface-area-to-volume ratio, which predisposes these dogs to hypothermia during anesthesia; (3) hematological differences such as a higher packed cell volume and lower serum protein compared with other dog breeds which may complicate interpretation of preanesthetic blood work; (4) Impaired biotransformation of drugs by the liver resulting in prolonged recovery from certain intravenous anesthetics, especially thiopental; and increased risks of drug interactions.
This is really an interesting thread. There was no propofol in my life as a vet.
A hazard I know of in anaesthesia is a patient who is really wound up as anaesthesia is induced. It takes more, then the "more" is too much. Seems like some of these malinois could be worked up in a clinical setting, especially if the owner was not present.
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