It is usually a drastic thing, the first dog that I experienced it with was fine on one night, we went tracking and then played ball very vigorously on a baseball field. The next morning I woke up to find him dead lame. Took him to the vet, had an x-ray and it was pano.
In all the times I have experienced it, usually there was very little warning. It really doesn't take a long time. I was able to "see it coming" by the time my most recent dog got over it for good, but it was a minute change in gait the day before the serious limp would show up.
Asprin is rough on the stomach, so don't do too much. Let him rest, he is likely to not overdo things right now anyway.
Hairy went through a bout of limping when he turned about four months old. Concerned, we took him to a vet and she had explained to us that Hairy was growing way too fast, causing his lameness. By the time Hairy was 6 months old he weighed in at 85 lbs and was the size of an adult dog. We had to change his food to slow his growth which really didn't help much. Today, being 18 months old, he hasn't grown much more. He weighs about 95lbs and is 27" at the wither. I've heard of other GSD's that have limped through their first year due to growing too quickly. I had never heard of Panno before.
My Tibetan mastiff bitch had a couple-month long bout with pano from about 6 to 8 months. (She's 22 months now.) It's pretty common with large breeds. We gave her Ascriptin, basically aspirin coated with Maalox, for the pain and inflamation and Glycoflex (a glucosamine supplement)for joint support. It worked well for her. As I recall, the dosage was one regular strength tablet per 25 lbs of dog (up to 3 tablets) every 12 hours for Ascriptin.
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