When I was giving Adequan injections, my vet had me give them in the the back of the rear leg muscle, alternating legs each injection. I could see a difference in a couple days, his movement was more fluid, and his stance was better. The muscle back there was also pretty hard to miss, you just have to make sure you don't hit the vein.
I also give Adequan IM, monthly or bimonthly, and have been for over a year. I had been using the leg muscles, alternating, but since he tore his CCL his leg muscles, especially on the effected side, have withered. So I talked to my vet and starting using the back muscles, just feeling for the spine and alternating sides, moving up and down the spine on either side. It has been working great!
It is not dangerous if given subcutaneously accidentally, it just wouldn't be absorbed the same way and probably wouldn't be quite as effective. I always make sure I draw back on the plunger a little after I insert the needle, to make sure I don't get blood return (indicating it's in a blood vessel, which is not where it belongs) and then give the dose. (That's my nursing training talking!) However, my dog is very well behaved during this procedure and knows to stay very still and then he'll get a tasty treat.
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